The study was carried out on 48 layer birds of above 2 months age that were divided into six groups consisting of 8 in each. Group 1 served as control, group 2 was treated with imidacloprid @ 200 ppm in feed, group 3 was treated with vitamin C @ 200 ppm in feed, group 4 was treated with both imidacloprid@200ppm and vitamin C 200ppm, group 5 was treated with Withania somnifera @ 500 ppm in feed and group 6 was treated with imidacloprid @ 200 ppm in feed + Vitamin C @ 200 ppm in feed + Withania somnifera @ 500 ppm in feed. Moderate immunosuppression was exhibited in both humeral as well as cell mediated immunities. The above study concluded that Imidacloprid insecticide has immunological deleterious effects in chickens targeting the humeral and cell mediated immune responses and vitamin E and selenium supplementation decreased the ill effects of Imidacloprid.
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